How to increase HDL cholesterol?

HDL cholesterol, the "good" cholesterol, can be increased through regular exercise, healthy fats like olive oil and fatty fish, weight loss, and lifestyle changes. Testing your levels regularly helps track progress and optimize your heart health strategy.

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Understanding HDL Cholesterol and Why It Matters

HDL (high-density lipoprotein) cholesterol is often called "good cholesterol" because it acts like a cleanup crew in your bloodstream. Unlike LDL cholesterol that can build up in your arteries, HDL actually removes excess cholesterol from your blood vessels and transports it to your liver for disposal. This protective function makes HDL a crucial player in cardiovascular health.

Research shows that for every 1 mg/dL increase in HDL cholesterol, cardiovascular disease risk decreases by 2-3%. However, about 20% of adults have HDL levels below the recommended range, putting them at increased risk for heart disease. Understanding your HDL levels through comprehensive testing is the first step toward optimizing this important biomarker.

What Are Optimal HDL Levels?

HDL cholesterol levels vary by sex due to hormonal differences. Women typically have higher HDL levels than men, partly due to estrogen's protective effects. Here's what the numbers mean:

HDL Cholesterol Level Categories

HDL levels should be interpreted alongside other cardiovascular risk factors and biomarkers.
HDL LevelCategoryRisk LevelAction Needed
Men: <40 mg/dL<40 mg/dL (men)LowHigh cardiovascular riskImmediate lifestyle changes recommended
Women: <50 mg/dL<50 mg/dL (women)LowHigh cardiovascular riskImmediate lifestyle changes recommended
40-59 mg/dL40-59 mg/dLBorderlineModerate riskFocus on diet and exercise improvements
≥60 mg/dL≥60 mg/dLOptimalProtectiveMaintain healthy habits

HDL levels should be interpreted alongside other cardiovascular risk factors and biomarkers.

While higher HDL is generally better, extremely high levels (above 100 mg/dL) may paradoxically increase cardiovascular risk in some individuals. This highlights the importance of regular monitoring and working with healthcare providers to understand your complete lipid profile.

Exercise: Your Most Powerful HDL Booster

Physical activity is one of the most effective ways to increase HDL cholesterol. Studies show that regular aerobic exercise can raise HDL levels by 5-10%, with some individuals experiencing even greater improvements. The key is consistency and finding activities you enjoy enough to maintain long-term.

Best Types of Exercise for HDL

  • Aerobic exercise: Aim for 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity cardio weekly
  • High-intensity interval training (HIIT): Can increase HDL by up to 10% in just 8-12 weeks
  • Resistance training: Combining strength training with cardio provides additional HDL benefits
  • Walking: Even 30 minutes daily can improve HDL levels by 5-7%

The intensity matters less than consistency. A 2019 study in the Journal of the American Heart Association found that people who exercised regularly for six months increased their HDL by an average of 6 mg/dL, regardless of whether they did moderate or vigorous exercise.

Dietary Strategies to Raise HDL Cholesterol

Your diet plays a crucial role in HDL production and function. While genetics influence baseline HDL levels, dietary changes can lead to meaningful improvements of 5-15% in most people.

Foods That Increase HDL

  • Fatty fish: Salmon, mackerel, and sardines provide omega-3 fatty acids that boost HDL
  • Olive oil: Extra virgin olive oil can increase HDL by 6-7% when replacing other fats
  • Nuts and seeds: Almonds, walnuts, and flaxseeds support healthy cholesterol levels
  • Avocados: Rich in monounsaturated fats that improve HDL function
  • Purple produce: Anthocyanins in berries, purple cabbage, and eggplant increase HDL by up to 13%

A Mediterranean-style diet, rich in these foods, has been shown to increase HDL levels by 10-15% while improving overall cardiovascular health markers. The PREDIMED study, involving over 7,000 participants, demonstrated that following a Mediterranean diet supplemented with extra virgin olive oil or nuts significantly increased HDL levels compared to a low-fat diet.

Foods and Habits to Avoid

Certain dietary choices can suppress HDL production or impair its function:

  • Trans fats: Found in processed foods, these can lower HDL by 20% or more
  • Excessive sugar: High sugar intake reduces HDL and increases triglycerides
  • Refined carbohydrates: White bread, pastries, and sugary drinks negatively impact HDL
  • Excessive alcohol: While moderate amounts may increase HDL, heavy drinking is harmful

Lifestyle Modifications for Better HDL

Beyond diet and exercise, several lifestyle factors significantly influence HDL cholesterol levels. Making strategic changes in these areas can provide additional HDL benefits and improve overall cardiovascular health.

Weight Management

Losing excess weight is one of the most effective ways to increase HDL cholesterol. Research shows that for every 7 pounds of weight loss, HDL typically increases by 1 mg/dL. Even modest weight loss of 5-10% of body weight can lead to significant improvements in HDL levels and function.

The relationship between weight and HDL is particularly important for those with metabolic syndrome or insulin resistance. These conditions often feature low HDL as a key component, and addressing weight can help break this cycle. If you're working on weight management and want to understand how it's affecting your metabolic health markers, comprehensive testing can provide valuable insights into your progress.

Quit Smoking and Manage Stress

Smoking is one of the worst things you can do for your HDL levels. It not only lowers HDL by 5-10% but also damages the HDL particles, making them less effective at removing cholesterol. The good news? HDL levels can increase by up to 10% within just 8 weeks of quitting smoking.

Chronic stress also negatively impacts HDL through increased cortisol production and inflammation. Stress management techniques that can help maintain healthy HDL levels include:

  • Regular meditation or mindfulness practice
  • Yoga or tai chi
  • Adequate sleep (7-9 hours nightly)
  • Social connections and support systems

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Natural Supplements That May Help

While lifestyle changes should be your primary focus, certain supplements have shown promise in raising HDL levels. Always consult with a healthcare provider before starting any supplement regimen, especially if you're taking medications.

Evidence-based supplements for HDL support include:

Remember that supplements work best when combined with a healthy lifestyle. They're not a substitute for proper diet and exercise but can provide additional support for those struggling to reach optimal HDL levels through lifestyle changes alone.

When to Consider Medical Intervention

If lifestyle modifications haven't sufficiently improved your HDL levels after 3-6 months, it may be time to discuss medical options with your healthcare provider. Some people have genetic factors that make it difficult to raise HDL naturally.

Medical interventions may include:

  • Prescription omega-3 fatty acids
  • Fibrates (particularly if triglycerides are also high)
  • Statins (which modestly increase HDL while lowering LDL)
  • PCSK9 inhibitors for those with familial cholesterol disorders

The decision to use medication should be based on your overall cardiovascular risk profile, not just HDL levels alone. This is why comprehensive lipid testing, including advanced markers like ApoA1 and ApoB, provides a more complete picture of your cardiovascular health.

Tracking Your Progress

Improving HDL cholesterol is a gradual process that requires patience and consistency. Most lifestyle interventions take 6-12 weeks to show measurable changes in HDL levels. Regular testing helps you understand what's working and adjust your approach as needed.

When monitoring your HDL improvement journey, consider tracking:

  • HDL cholesterol levels every 3-6 months
  • Complete lipid panel including triglycerides and LDL
  • Advanced markers like ApoA1 (the main protein in HDL particles)
  • Inflammatory markers like hs-CRP that affect HDL function
  • Metabolic markers if you have diabetes or prediabetes

Understanding your complete cardiovascular picture helps you and your healthcare provider make informed decisions about your heart health strategy. If you have existing blood test results, you can get a comprehensive analysis of your cardiovascular biomarkers using SiPhox Health's free upload service to better understand your current HDL status and receive personalized recommendations.

The Bottom Line on Raising HDL

Increasing HDL cholesterol is one of the most impactful steps you can take for your cardiovascular health. While genetics play a role in your baseline HDL levels, research consistently shows that lifestyle modifications can lead to meaningful improvements for most people.

The most effective approach combines regular aerobic exercise, a Mediterranean-style diet rich in healthy fats, weight management, and stress reduction. These changes not only boost HDL but improve overall metabolic health, reducing your risk of heart disease, diabetes, and other chronic conditions.

Remember that improving HDL is a marathon, not a sprint. Focus on sustainable changes you can maintain long-term rather than dramatic short-term interventions. With patience, consistency, and regular monitoring, you can achieve and maintain healthy HDL levels that support your cardiovascular health for years to come.

References

  1. Kodama S, Tanaka S, Saito K, et al. Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Archives of Internal Medicine. 2007;167(10):999-1008.[PubMed][DOI]
  2. Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. New England Journal of Medicine. 2018;378(25):e34.[PubMed][DOI]
  3. Gepner AD, Piper ME, Johnson HM, et al. Effects of smoking and smoking cessation on lipids and lipoproteins: outcomes from a randomized clinical trial. American Heart Journal. 2011;161(1):145-151.[PubMed][DOI]
  4. Mann S, Beedie C, Jimenez A. Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Medicine. 2014;44(2):211-221.[PubMed][DOI]
  5. Kelley GA, Kelley KS. Aerobic exercise and HDL2-C: a meta-analysis of randomized controlled trials. Atherosclerosis. 2006;184(1):207-215.[PubMed][DOI]
  6. Barter P, Genest J. HDL cholesterol and ASCVD risk stratification: A debate. Atherosclerosis. 2019;283:7-12.[PubMed][DOI]

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Frequently Asked Questions

How can I test my HDL cholesterol at home?

You can test your HDL cholesterol at home with SiPhox Health's Heart & Metabolic Program. This CLIA-certified program includes HDL cholesterol testing along with comprehensive cardiovascular biomarkers, providing lab-quality results from the comfort of your home.

How long does it take to increase HDL cholesterol naturally?

Most people see measurable improvements in HDL levels within 6-12 weeks of making lifestyle changes. Exercise can show benefits in as little as 8 weeks, while dietary changes typically take 8-12 weeks to significantly impact HDL levels.

Can you have HDL cholesterol that's too high?

Yes, extremely high HDL levels (above 100 mg/dL) may paradoxically increase cardiovascular risk in some individuals. This is why it's important to focus on overall cardiovascular health rather than just maximizing HDL numbers.

What's the single best exercise to increase HDL?

While any regular aerobic exercise helps, high-intensity interval training (HIIT) shows the most dramatic HDL improvements, with studies showing increases of up to 10% in just 8-12 weeks. However, the best exercise is the one you'll do consistently.

Do HDL-raising supplements really work?

Some supplements like niacin, omega-3 fatty acids, and plant sterols have shown modest HDL benefits in clinical studies. However, they work best when combined with lifestyle changes and should not replace a healthy diet and regular exercise.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
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Advisor

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Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
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Advisor

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His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
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Advisor

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In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
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View Details
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Health Programs Lead, Health Innovation

Dr. Tsogbayar leverages her clinical expertise to develop innovative health solutions and evidence-based coaching. Dr. Tsogbayar previously practiced as a physician with a comprehensive training background, developing specialized expertise in cardiology and emergency medicine after gaining experience in primary care, allergy & immunology, internal medicine, and general surgery.

She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
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Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details