Lower your heart disease risk

Lower your heart disease risk

See results in 6 weeks or less.

  • Comprehensive blood biomarker tests every 6 weeks. Tests include advanced lipid, metabolic fitness, inflammation, liver, kidney, and thyroid biomarkers. Up to 8 tests per year.
  • Personalized action plan based on your unique biology, built by clinical experts.
  • Optimize for the lowest effective dose of lipid-lowering medication as needed.
  • $99 per month all included.

HSA / FSA cards accepted

Lower your risk of heart and metabolic disease

We will track how your body responds to your medication, lifestyle, diet, and supplements to help you feel better today and increase your healthspan.

Lower your risk of heart and metabolic diseaseLower your risk of heart and metabolic disease

Heart and metabolic health is not just about lipids

  • Lp(a)
  • ApoB
  • ApoA1
  • HbA1C
  • HDL-C
  • LDL-C
  • Cholesterol (total)
  • Fasting Insulin
  • Fasting Glucose
  • hsCRP
  • Homocysteine
  • Triglycerides
  • Blood Pressure
  • Creatinine
  • BUN
  • Bilirubin
  • Triglyceride/HDL-C Ratio
  • TSH
  • eGFR
  • Body Composition
  • ALT
  • AST
Responsive medication management

Responsive medication management

SiPhox will help you access the right lipid-lowering medications for you if needed.

  • Initiate and manage your statin or ezetemibe to the lowest effective dose using home test results
  • Send your prescription to your local pharmacy
  • Chat with a clinician any time

How it works

Improving your heart health and longevity with SiPhox is convenient, affordable and data-driven

Get a test delivered straight to your door
Send your sample to our lab in the prepaid return envelope
View results alongside personalized insights and recommendations written by our expert clinicians.
Option to sign up for live 1:1 call with our doctors to review results and recommendations. Coaching also available
Receive prescription for a statin or ezetimibe if needed
Retake tests as often as every 6 weeks to assess changes


Comprehensive test kit

Comprehensive test kit

You will receive our convenient and comprehensive heart and metabolic focused blood test kit as often as once every 6 weeks.

A tool for every step of your health journey:

  • Collect your sample in under 10 minutes. Our care team can walk you through the collection process on a live call.
  • Results with personalized insights and recommendations written by our expert clinicians in 3-5 days from sending in sample.
  • Additional coaching available.
  • COMING SOON: Prescription management, tuned according to your bloodwork.
Holistically empowering you to improve your health

Holistically empowering you to improve your health

A responsive coaching and affiliated clinical team will help make sure your regular testing has direct and fast impact on your healthcare and lifestyle choices.

What is ApoB?

What is ApoB?

Unlike most standard lab tests, SiPhox’s Heart Health test includes ApoB in addition to LDL-C. ApoB is a structural protein on all potentially atherogenic (plaque-forming) particles. Many studies suggest that ApoB may be more useful than LDL-C in assessing risks relating to coronary heart disease, diabetes, and other conditions.

What is Lp(a)?

What is Lp(a)?

Lipoprotein(a), or Lp(a), is an underappreciated risk factor for developing heart attacks or strokes early in middle age.

Lp(a) is more common than many people realize: about one in five people (20% of the population) worldwide have high Lp(a) levels, including 63 million people in the US alone.

Which heart and metabolic health plan is right for you?

We offer a range of plans that suit your needs, whether you want to just get a snapshot of your health or you're ready to take full control of your health span.

  • One-Time Panel and Assessment


    $295per assessment

    Billed one-time

    Check your heart and metabolic health related biomarkers today and get actionable insights to improve risk factors.

  • Best Value

    Annual Heart & Metabolic Blueprint


    $990every year

    Billed $990 yearly
    Save up to 58% per kit

    Receive regular tests, in-depth assessments, and prescription management for the lowest price on the market.

  • Monthly Heart & Metabolic Blueprint


    $99every month

    Extend your healthspan

    Receive regular tests, in-depth assessments, and prescription management with no long term commitment.

Why the Heart Health Blueprint?

An extensive analysis of thousands of at-home blood test results revealed a common concern: many of our customers are at risk for heart and metabolic diseases. We decided to tackle the issue head-on with our Blueprint Program.

Check out this unsolicited Trustpilot review from a customer who recently made a life-saving discovery with SiPhox.

Over 20,000 customers and counting

This site changed my life!

This site changed my life. Regular medicine has said my slightly elevated cholesterol was ok for my age and fitness level; boy they were wrong! This test showed bad ApoA&B levels, causing me to get a calcium test and CT angiogram. Long story short, I was developing Coronary Artery Disease with no symptoms, all while running half marathons and looking “normal”. 2 stents later, I’m back running and have all my bookmakers in check. Traditional medicine is not working! This service allows you to take control of your health. It saved my life!

M T,

12. 24. 2023

The SiPhox virtuous cycle

Regular, convenient, affordable testing of your blood biomarkers, integrated with a platform that manages your medications and tracks your health.

The SiPhox virtuous cycle

Who is the SiPhox Heart Health Blueprint for?

If you want better insight into your overall health

Test for the most important heart and safety metrics with one at-home test, including those often missed by traditional testing.

If you want a systems-based approach to health and longevity

See how you are progressing each month, and make sure you are taking the right steps to improve

If you want to make data-driven decisions to guide treatment and lifestyle changes

Start getting testing and insight-driven monthly prescriptions in one convenient platform

Frequently asked questions:

If your question is not found below, please feel free to email us your question at

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